{"id":5,"date":"2021-08-12T07:46:37","date_gmt":"2021-08-12T07:46:37","guid":{"rendered":"http:\/\/localhost\/labortech\/?page_id=5"},"modified":"2022-01-20T14:45:00","modified_gmt":"2022-01-20T14:45:00","slug":"home","status":"publish","type":"page","link":"http:\/\/iap.iisc.ac.in\/~partha\/","title":{"rendered":"Home"},"content":{"rendered":"\n<!--hero section start-->\n<section class=\"home_banner banner p-0 pos-r fullscreen-banner\">\n<div class='white' style='background:rgb(243, 248, 253); border:solid 1px #f0f0f0; border-radius:5px; padding:0px 0px 0px 0px;'>\n<div id='sample_slider' class='owl-carousel sa_owl_theme autohide-arrows' data-slider-id='sample_slider' style='visibility:hidden;'>\n<div id='sample_slider_slide01' class='sa_hover_container' style='padding:0% 0%; margin:0px 0%; background-color:rgb(245, 248, 253); '><div class=\"align-center pt-0\">\r\n<div class=\"container\">\r\n<div class=\"row\">\r\n<div class=\"col-md-8\">\r\n<h1 class=\"mb-4 text-black\">Classical & Quantum Optics<\/h1>\r\n<p class=\"lead font-w-5 text-black\">Classical and Quantum Optics is the first text to cover classical and quantum optics as a single subject with the premise that genuine understanding of light requires mastery of both fields. It addresses all aspects of light equally, including geometric optics, wave optics, electromagnetic optics, and quantum optics. This timely book supplies the tools needed to fully explore the behavior of light.<\/p>\r\n<\/div>\r\n<div class=\"col-md-1\">\u00a0<\/div>\r\n<div class=\"col-md-3\"><a href=\"https:\/\/aip.scitation.org\/isbn\/9780735423367\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-52\" src=\"http:\/\/iap.iisc.ac.in\/~partha\/wp-content\/uploads\/2022\/01\/CQO1-300x184.jpg\" alt=\"\" width=\"140\" height=\"230\" \/><\/a><\/div>\r\n<\/div>\r\n<\/div>\r\n<\/div><\/div>\n<div id='sample_slider_slide02' class='sa_hover_container' style='padding:0% 0%; margin:0px 0%; '><div class=\"align-center pt-0\">\r\n<div class=\"container\">\r\n<div class=\"row\">\r\n<div class=\"col-md-8\">\r\n<h1 class=\"mb-4 text-black\">Light Sheet Microscopy and Imaging<\/h1>\r\n<p class=\"lead font-w-5 text-black\">Light Sheet Microscopy and Imaging introduces the fundamentals and important advancements at the frontiers of optical physics and applied sciences. It presents coherent, in-depth explanations of different variants of light sheet microscopes beginning from the basics of light. This emerging technology has an impact on a range of disciplines from nanophysics (nanolithography) to biophysics (imaging, cell biology, developmental biology, and biotechniques) and is destined to influence every field of science and engineering.<\/p>\r\n<\/div>\r\n<div class=\"col-md-1\">\u00a0<\/div>\r\n<div class=\"col-md-3\"><a href=\"https:\/\/aip.scitation.org\/isbn\/9780735423367\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-52\" src=\"http:\/\/iap.iisc.ac.in\/~partha\/wp-content\/uploads\/2022\/01\/LSMI.jpeg\" alt=\"\" width=\"140\" height=\"199\" \/><\/a><\/div>\r\n<\/div>\r\n<\/div>\r\n<\/div><\/div>\n<div id='sample_slider_slide03' class='sa_hover_container' style='padding:0% 0%; margin:0px 0%; background-color:rgb(245, 248, 253); '><!--div class=\"video-wrapper\"><iframe  style=\"width:100%; height:100%\"\r\nsrc=\"https:\/\/www.youtube.com\/embed\/tgbNymZ7vqY?playlist=tgbNymZ7vqY&loop=1\">\r\n<\/iframe> <\/div!-->\r\n<div class=\"align-center pt-0\">\r\n<div class=\"container\">\r\n<div class=\"row\">\r\n<div class=\"col-lg-6 col-md-10 col-12\">\r\n<h1 class=\"mb-4 text-black\">iLIFE Cytometry<\/h1>\r\n<p class=\"lead font-w-5 text-black\">Modern Biology and Medicine needs a single-stop solution for most of its analysis and diagnostic requirements. Nanobioimaging lab at Indian Institute of Science has developed a versatile, multifunctional optical iLIFE system to facilitate health-care. We envision applications ranging from fundamental biology to clinical diagnosis, be it hematology, pathology, oncology or drug-discovery.<\/p>\r\n<\/div>\r\n<div class=\"col-lg-6 col-md-6 col-12 video-wrapper1\"><iframe style=\"width: 100%; height: 220px;\" src=\"https:\/\/www.youtube.com\/embed\/pMBKMpyJNlQ?loop=1\"><\/iframe><\/div>\r\n<\/div>\r\n<\/div>\r\n<\/div><\/div>\n<div id='sample_slider_slide04' class='sa_hover_container' style='padding:0% 0%; margin:0px 0%; '><!--div class=\"video-wrapper\"><iframe  style=\"width:100%; height:100%\"\r\nsrc=\"https:\/\/www.youtube.com\/embed\/tgbNymZ7vqY?playlist=tgbNymZ7vqY&loop=1\">\r\n<\/iframe> <\/div!-->\r\n<div class=\"align-center pt-0\">\r\n<div class=\"container\">\r\n<div class=\"row\">\r\n<div class=\"col-lg-6 col-md-10 col-12\">\r\n<h1 class=\"mb-4 text-black\">Super-resolution Optical Microscopy<\/h1>\r\n<p class=\"lead font-w-5 text-black\">Often, we are faced with the question of how well we can resolve features in an image. The answer lies in the diffraction of light and it is largely decided by the fluorescing single molecule, which limit its size to half the wavelength of light (size ~ \u03bb\/2). We ask, how close we can approach the Single Molecule Limit (the actual size of single molecules). Mondal Lab @ Indian Institute of Science has developed new imaging systems (SMILE and POSSIBLE) to address these open questions.<\/p>\r\n<\/div>\r\n<div class=\"col-lg-6 col-md-6 col-12 video-wrapper1\"><iframe style=\"width: 100%; height: 220px;\" src=\"https:\/\/www.youtube.com\/embed\/I6mLwbe6lvk?loop=1\"><\/iframe><\/div>\r\n<\/div>\r\n<\/div>\r\n<\/div><\/div>\n<div id='sample_slider_slide05' class='sa_hover_container' style='padding:0% 0%; margin:0px 0%; background-color:rgb(245, 248, 253); '><div class=\"align-center pt-0\">\r\n<div class=\"container\">\r\n<div class=\"row\">\r\n<div class=\"col-md-8\">\r\n<h1 class=\"mb-4 text-black\">Light Sheet Optical Tweezer<\/h1>\r\n<p class=\"lead font-w-5 text-black\">Imaging, reconstructing tissue or an entire organ from the basic unit of life i.e, cell. This requires arranging cells in precise pattern similar to that naturally occurs during early organ development. This is precisely made possible by a recently developed Light sheet optical tweezer i.e, (LOT). Mondal labs at Indian Institute of Science has demonstrated the technique (LOT) by trapping, patterning and culturing live cells.<\/p>\r\n<\/div>\r\n<div class=\"col-md-1\">\u00a0<\/div>\r\n<div class=\"col-md-3\"><a href=\"https:\/\/aip.scitation.org\/isbn\/9780735423367\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-52\" src=\"http:\/\/iap.iisc.ac.in\/~partha\/wp-content\/uploads\/2022\/02\/LOT.png\" alt=\"\" width=\"140\" height=\"230\" \/><\/a><\/div>\r\n<\/div>\r\n<\/div>\r\n<\/div><\/div>\n<\/div>\n<\/div>\n<script type='text\/javascript'>\n\tjQuery(document).ready(function() {\n\t\tjQuery('#sample_slider').owlCarousel({\n\t\t\titems : 1,\n\t\t\tsmartSpeed : 500,\n\t\t\tautoplay : true,\n\t\t\tautoplayTimeout : 4800,\n\t\t\tautoplayHoverPause : true,\n\t\t\tsmartSpeed : 500,\n\t\t\tfluidSpeed : 500,\n\t\t\tautoplaySpeed : 500,\n\t\t\tnavSpeed : 500,\n\t\t\tdotsSpeed : 500,\n\t\t\tloop : true,\n\t\t\tnav : true,\n\t\t\tnavText : ['Previous','Next'],\n\t\t\tdots : false,\n\t\t\tresponsiveRefreshRate : 200,\n\t\t\tslideBy : 1,\n\t\t\tmergeFit : true,\n\t\t\tautoHeight : false,\n\t\t\tmouseDrag : false,\n\t\t\ttouchDrag : false\n\t\t});\n\t\tjQuery('#sample_slider').css('visibility', 'visible');\n\t\tsa_resize_sample_slider();\n\t\twindow.addEventListener('resize', sa_resize_sample_slider);\n\t\tfunction sa_resize_sample_slider() {\n\t\t\tvar min_height = '20';\n\t\t\tvar win_width = jQuery(window).width();\n\t\t\tvar slider_width = jQuery('#sample_slider').width();\n\t\t\tif (win_width < 480) {\n\t\t\t\tvar slide_width = slider_width \/ 1;\n\t\t\t} else if (win_width < 768) {\n\t\t\t\tvar slide_width = slider_width \/ 1;\n\t\t\t} else if (win_width < 980) {\n\t\t\t\tvar slide_width = slider_width \/ 1;\n\t\t\t} else if (win_width < 1200) {\n\t\t\t\tvar slide_width = slider_width \/ 1;\n\t\t\t} else if (win_width < 1500) {\n\t\t\t\tvar slide_width = slider_width \/ 1;\n\t\t\t} else {\n\t\t\t\tvar slide_width = slider_width \/ 1;\n\t\t\t}\n\t\t\tslide_width = Math.round(slide_width);\n\t\t\tvar slide_height = '0';\n\t\t\tif (min_height == 'aspect43') {\n\t\t\t\tslide_height = (slide_width \/ 4) * 3;\t\t\t\tslide_height = Math.round(slide_height);\n\t\t\t} else if (min_height == 'aspect169') {\n\t\t\t\tslide_height = (slide_width \/ 16) * 9;\t\t\t\tslide_height = Math.round(slide_height);\n\t\t\t} else {\n\t\t\t\tslide_height = (slide_width \/ 100) * min_height;\t\t\t\tslide_height = Math.round(slide_height);\n\t\t\t}\n\t\t\tjQuery('#sample_slider .owl-item .sa_hover_container').css('min-height', slide_height+'px');\n\t\t}\n\t\tvar owl_goto = jQuery('#sample_slider');\n\t\tjQuery('.sample_slider_goto1').click(function(event){\n\t\t\towl_goto.trigger('to.owl.carousel', 0);\n\t\t});\n\t\tjQuery('.sample_slider_goto2').click(function(event){\n\t\t\towl_goto.trigger('to.owl.carousel', 1);\n\t\t});\n\t\tjQuery('.sample_slider_goto3').click(function(event){\n\t\t\towl_goto.trigger('to.owl.carousel', 2);\n\t\t});\n\t\tjQuery('.sample_slider_goto4').click(function(event){\n\t\t\towl_goto.trigger('to.owl.carousel', 3);\n\t\t});\n\t\tjQuery('.sample_slider_goto5').click(function(event){\n\t\t\towl_goto.trigger('to.owl.carousel', 4);\n\t\t});\n\t\tvar resize_139 = jQuery('.owl-carousel');\n\t\tresize_139.on('initialized.owl.carousel', function(e) {\n\t\t\tif (typeof(Event) === 'function') {\n\t\t\t\twindow.dispatchEvent(new Event('resize'));\n\t\t\t} else {\n\t\t\t\tvar evt = window.document.createEvent('UIEvents');\n\t\t\t\tevt.initUIEvent('resize', true, false, window, 0);\n\t\t\t\twindow.dispatchEvent(evt);\n\t\t\t}\n\t\t});\n\t});\n<\/script>\n\n<\/section>\n\n<!--hero section end-->\n\n\n<!--body content start-->\n\n<div class=\"page-content\">\n\n<!--feature start-->\n\n<section class=\"pb-0 pt-1\">\n  <div class=\"container\">\n<h2 class=\"title\">Advances<\/h2>\n\t<ul class=\"advance_list\">\n\t\t<li><a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2021.07.05.451038v1?rss=1\"> Lightsheet Optical Tweezer for Particle &#038; Cell Manipulation<\/a><\/li>\n\t\t<li><a href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0242452\">POSSIBLE Super-resolution Microscopy (resolution < 10nm), PLoS One<\/a><\/li>\n\t\t<li><a href=\"https:\/\/www.nature.com\/articles\/s41598-021-86951-3 \">Light Sheet based OVSS) for interrogating multicellular organisms, Nature Sci. Rep.<\/a><\/li>\n\t<\/ul> \n  <\/div>\n<\/section>\n<!--feature end-->\n \n \n<section class=\"pb-0 pt-4\">\n\t<div class=\"container\">\n\t\t<p>Nanobioimaging lab peruses both fundamental and applied research in the broad area of Applied Physics and Biophysics. This research areas include, Single Molecule Physics and Biology, Light Sheet Microscopy, Optical Traps, Super-resolution Microscopy, Nano Fluidics and Devices, Optical microscopy, Fluorescence microscopy, Ultrafast imaging, Imaging Cytometry and Multi-dimensional image reconstruction. The research work is focused on the development of optical microscopes that is capable of spatio-temporal super-resolution and optical systems design. The lab is actively engaged in developing new optical imaging techniques based on single molecules and Light-sheets for applications in physical and biological sciences. Some of the ongoing techniques include: Optical Super-Resolution Microscopy, Optical Tweezers for Cell Biophysics, Light Sheet Imaging Cytometry &#8211; LIVE, Nanolithography and Nano-fluidics, iLIFE Imaging Cytometry &#8211; Imaging on the go, Disease Biology (Dengue, Influenza and Cancer). The main thrust is to develop and extend these advanced techniques for applications in Fundamental Physics and Biology.<\/p>\n\t<\/div>\n<\/section>\n","protected":false},"excerpt":{"rendered":"<p>Advances Lightsheet Optical Tweezer for Particle &#038; Cell Manipulation POSSIBLE Super-resolution Microscopy (resolution < 10nm), PLoS One Light Sheet based OVSS) for interrogating multicellular organisms, Nature Sci. Rep. Nanobioimaging lab peruses both fundamental and applied research in the broad area of Applied Physics and Biophysics. 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