Research Interest
The Frontiers in Imaging Spectroscopy and Theranostics (FIST) lab develops novel systems for improved sensing, diagnosis, and therapeutic approaches, targeted towards biological and medical theranostics. Specific interests include
- non-invasive investigation of physiological, metabolic, and molecular processes in tissues at unprecedented depth to resolution ratio to solve unmet needs in medicine and biology (with special focus on cancer, cardiovascular and diabetes)
- real-time computational methods in medical image reconstruction/analysis, with special focus on photoacoustics/optoacoustic imaging
- Understand fundamental light-matter interaction with polarized photoacoustic effect, and its application in chiral biomolecular sensing
- Non-invasive optical glucose sensing methods and diabetes management
Biographical Sketch
- Jaya Prakash received the B.Tech. degree in information technology from the Amrita School of Engineering, Bengaluru, India, in 2010, and the M.Sc. degree in engineering and the Ph.D. degree in medical imaging from the Indian Institute of Science, Bengaluru, in 2012 and 2014, respectively.
- Prior to taking up his current position as an Assistant Professor with the Department of Instrumentation and Applied Physics, Indian Institute of Science, he was the Group Leader of the Computational Data Analytics Group, Institute for Biological and Medical Imaging, Helmholtz Zentrum Munich, Oberschleißheim, Germany.
- His research interests are image reconstruction, inverse problems, optoacoustic imaging, biomedical instrumentation, and biomedical optics.
Select Publications
- Swathi Padmanabhan, and Jaya Prakash, “Deep tissue sensing of chiral molecules using polarization enhanced photoacoustics,” Science Advances 11(12), eado8012 (2025).
- Swathi Padmanabhan, Sarikonda Aryan Shashank, Rajesh Srinivasan, and Jaya Prakash, “Optoacousto-fluidics Based Optical Rotation Measure for Blood Glucose Sensing,” IEEE Transactions on Biomedical Engineering 2025 (in press).
- Hemanth S. Nakshatri, and Jaya Prakash, “Complex valued long short term memory based architecture for frequency domain photoacoustic imaging,” IEEE Transactions on Computational Imaging 9, 551-564 (2023).
- Arumugaraj M, Vipul Gujrati, Vasilis Ntziachristos, and Jaya Prakash, “Deep learning methods hold promise for light fluence compensation in three-dimensional optoacoustic imaging,” Journal of Biomedical Optics 27(10), 106004 (2022).
- Jaya Prakash*, Mir Mehdi Seyedebrahimi*, Ara Ghazaryan*, Jaber Malekzadeh-Najafabadi, Vipul Gujrati, and Vasilis Ntziachristos, “Short wavelength optoacoustic spectroscopy based on water muting,” Proceedings of the National Academy of Sciences 117(8), 4007-4014 (2020).
- Jaya Prakash*, Dween Sanny*, Sandeep K. Kalva, Manojit Pramanik, and Phaneendra K. Yalavarthy, ”Fractional regularization to improve photoacoustic tomographic image reconstruction,” IEEE Transactions on Medical Imaging 38(8), 1935-1947 (2019).